5-HTP (5-hydroxytryptophan)


5-HTP is a compound that is converted to a chemical (serotonin) in the brain. Among other roles, serotonin is thought to be involved in reduced pain sensitivity. Individuals take this supplement to try to increase tolerance to pain during intense exercise, and to improve endurance.

Research Results:

Well-designed research studies do not support that 5-HTP increases tolerance to pain or improves endurance.

Return to Supplement Guide

Take Our Survey


We need your help! Periodically we conduct a survey of our visitors and use the results to help guide our planning process for future programming. We really want to know what you think, and your answers will help us improve the Shape Up America! organization. Please take a few minutes to share your questions, thoughts and ideas. Your responses will be kept strictly confidential.

Btn Click Here

Donate to SUA


Please consider a donation to Shape Up America! Your tax-deductible contribution helps us develop new initiatives to address the problem of obesity in America.

Btn Click Here